Head of msat manufacturing science and technology amsterdam commercial cell therapy facility Vacatures

Over de vacature

Overview

In this role you drive the MSAT strategy for Kite's Amsterdam commercial cell therapy facility, leading a high-performing team of managers and senior technical leaders. You ensure robust, compliant manufacturing, technology transfer, and lifecycle activities in a GMP environment, while partnering across functions to deliver reliable patient-facing operations. You shape governance, risk-based decisions, and regulatory readiness, enabling scalable, efficient production. You will influence site and network priorities and advance operational excellence in cell therapy manufacturing.

Verantwoordelijkheden

• Define and execute the site MSAT strategy, operating plan, budget, workforce model, governance, capabilities, and performance metrics
• Build and develop an inclusive, high-performing organization of managers and senior technical leaders
• Lead technical governance, escalation, and risk-based decisions for manufacturing support, process performance, validation, and high-impact issues
• Oversee shop-floor support, investigations, root-cause analysis, CAPAs, laboratory studies, and process improvements
• Lead technology transfer and lifecycle management including facility fit, risk assessment, control strategy, comparability, qualification, PPQ readiness, training, and sustained post-transfer performance
• Govern the validation lifecycle using process knowledge, statistics, digital capabilities, and data science to improve robustness, yield, cycle time, and proactive risk management
• Set direction for MSAT laboratories and operational automation, ensuring validated systems, data integrity, and manufacturing integration
• Lead technical content and readiness for regulatory submissions, health-authority inquiries, inspections, and commitments
• Represent site priorities in global forums and collaborate across Manufacturing, Quality, Supply Chain, Facilities & Engineering, Product Development, Regulatory Affairs, and global MSAT
• Sponsor cross-site initiatives that advance operational excellence, technology modernization, and long-term site and network competitiveness

Belangrijkste vereisten

• PhD/MS in relevant Science/Engineering with biopharmaceutical manufacturing or technology transfer experience OR BA/BS with relevant experience OR High School Diploma with significant experience in biopharmaceutical manufacturing

• Significant leadership experience in a commercial GMP environment with accountability for technical performance and delivery through managers and senior professionals

• Executive-level communication and influencing skills

• Strong collaboration across cross-functional teams

• Problem-solving mindset with ability to prioritize and drive results

• Deep GMP knowledge and experience in cell therapy, biologics, aseptic processing, single-use systems, and automation

• Technology transfer, process validation, comparability, and control strategy

• Validation lifecycle management, data science, statistics, and digital capabilities

Over de vacature

Overview

In this role you drive the MSAT strategy for Kite's Amsterdam commercial cell therapy facility, leading a high-performing team of managers and senior technical leaders. You ensure robust, compliant manufacturing, technology transfer, and lifecycle activities in a GMP environment, while partnering across functions to deliver reliable patient-facing operations. You shape governance, risk-based decisions, and regulatory readiness, enabling scalable, efficient production. You will influence site and network priorities and advance operational excellence in cell therapy manufacturing.

Verantwoordelijkheden

• Define and execute the site MSAT strategy, operating plan, budget, workforce model, governance, capabilities, and performance metrics
• Build and develop an inclusive, high-performing organization of managers and senior technical leaders
• Lead technical governance, escalation, and risk-based decisions for manufacturing support, process performance, validation, and high-impact issues
• Oversee shop-floor support, investigations, root-cause analysis, CAPAs, laboratory studies, and process improvements
• Lead technology transfer and lifecycle management including facility fit, risk assessment, control strategy, comparability, qualification, PPQ readiness, training, and sustained post-transfer performance
• Govern the validation lifecycle using process knowledge, statistics, digital capabilities, and data science to improve robustness, yield, cycle time, and proactive risk management
• Set direction for MSAT laboratories and operational automation, ensuring validated systems, data integrity, and manufacturing integration
• Lead technical content and readiness for regulatory submissions, health-authority inquiries, inspections, and commitments
• Represent site priorities in global forums and collaborate across Manufacturing, Quality, Supply Chain, Facilities & Engineering, Product Development, Regulatory Affairs, and global MSAT
• Sponsor cross-site initiatives that advance operational excellence, technology modernization, and long-term site and network competitiveness

Belangrijkste vereisten

• PhD/MS in relevant Science/Engineering with biopharmaceutical manufacturing or technology transfer experience OR BA/BS with relevant experience OR High School Diploma with significant experience in biopharmaceutical manufacturing

• Significant leadership experience in a commercial GMP environment with accountability for technical performance and delivery through managers and senior professionals

• Executive-level communication and influencing skills

• Strong collaboration across cross-functional teams

• Problem-solving mindset with ability to prioritize and drive results

• Deep GMP knowledge and experience in cell therapy, biologics, aseptic processing, single-use systems, and automation

• Technology transfer, process validation, comparability, and control strategy

• Validation lifecycle management, data science, statistics, and digital capabilities